A deep-dive comparison of four non-GLP-1 metabolic peptides: AOD-9604 (growth hormone lipolytic fragment), MOTS-c (mitochondrial AMPK activator), 5-Amino-1MQ (NNMT inhibitor), and Adipotide (vascular-targeted fat destruction). Mechanisms, research data, and head-to-head comparison.
A deep-dive into neuroprotective peptide research covering Cerebrolysin’s neurotrophic factor mimicry, Selank’s GABAergic modulation, Semax’s BDNF upregulation, Cortagen’s bioregulation, PE-22-28’s TREK-1 blocking, and P21’s CNTF-derived neurogenesis.
A deep-dive comparison of four wound healing peptides — BPC-157, TB-500, GHK-Cu, and LL-37 — examining their distinct mechanisms in angiogenesis, cell migration, collagen remodeling, and antimicrobial defense across the four phases of tissue repair.
A deep-dive into HPG axis peptide research: how kisspeptin’s 2003 discovery revealed the GnRH pulse generator, the paradox of continuous vs pulsatile gonadorelin, KNDy neuron mechanisms, and kisspeptin’s emerging role in fertility research including IVF triggering.
What does research show about stopping peptide administration? This article examines discontinuation effects across GH secretagogues, BPC-157, melanocortin peptides, and bioregulators — covering rebound phenomena, healing persistence, receptor tolerance, and cycling concepts.
GHK-Cu research extends far beyond cosmetics. Explore the science of copper peptides in wound healing, lung remodeling, anti-fibrotic effects, gene expression modulation, and neuroprotective research — with verified citations.
A deep-dive into thymus-derived peptides and immunosenescence research — thymic involution with age, Thymosin Alpha-1’s FDA orphan drug status and T-cell effects, Thymulin’s zinc-dependent modulation, and the broader landscape of immune aging.
A deep-dive into three peptides investigated for gastrointestinal applications — BPC-157’s cytoprotective mechanisms, KPV’s NF-kB modulation in colitis models, and LL-37’s dual role in gut defense and immune regulation.
An accessible guide to antimicrobial peptide (AMP) research, covering how LL-37 kills bacteria via membrane disruption, KPV suppresses inflammation through NF-kB inhibition, and why AMPs may help address the antibiotic resistance crisis.
A deep-dive research guide to Orexin B (hypocretin-2), covering its OX2R receptor selectivity, structural differences from Orexin A, narcolepsy connection, metabolic research on obesity resistance, and role in mesolimbic reward signaling.
